产品货号：
JN1654
中文名称：
重组人LOXL2(类赖氨酰氧化酶2)(赖氨酰氧化酶样蛋白2)
英文名称：
Recombinant Human Lysyl Oxidase Homolog 2
产品规格：
10μg|50μg|500μg|1mg
发货周期：
1～3天
产品价格：
询价
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Gln26-Gln774在C端带Avi-His标签。
LOXL2质量控制：＞95%(还原性SDS-PAGE)
LOXL2制剂：液体
LOXL2保存：收到货后请置于-20℃，可保存6个月，避免反复冻融。
关于LOXL2：
Lysyl oxidase homolog 2 is a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family. LOXL2 can also crosslink collagen type IV and hence influence the sprouting of new blood vessels. LOXL2 is an enzyme that is up-regulated in several types of cancer and is associated with a poorer prognosis. LOXL2 changes the structure of histonesand thus changes the shape of the cells, making it easier for the cancer cells to metastasize.
相关搜索：重组人LOXL2(类赖氨酰氧化酶2)(赖氨酰氧化酶样蛋白2)，Recombinant Human Lysyl Oxidase Homolog 2
LOXL2质量控制：＞95%(还原性SDS-PAGE)
LOXL2制剂：液体
LOXL2保存：收到货后请置于-20℃，可保存6个月，避免反复冻融。
关于LOXL2：
Lysyl oxidase homolog 2 is a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family. LOXL2 can also crosslink collagen type IV and hence influence the sprouting of new blood vessels. LOXL2 is an enzyme that is up-regulated in several types of cancer and is associated with a poorer prognosis. LOXL2 changes the structure of histonesand thus changes the shape of the cells, making it easier for the cancer cells to metastasize.
相关搜索：重组人LOXL2(类赖氨酰氧化酶2)(赖氨酰氧化酶样蛋白2)，Recombinant Human Lysyl Oxidase Homolog 2